Neck wrinkles are one of the signs of aging that appear due to accumulated factors such as decreased skin elasticity, repetitive facial movements, and exposure to ultraviolet rays. Compared to other areas of the face, the skin on the neck has fewer sebaceous glands and is thinner, so wrinkles form more quickly. Once neck wrinkles have formed, it is difficult to improve them with routine skin care alone, so professional treatment is often considered. It is especially difficult to remove neck wrinkles that have appeared since childhood.
One of the ways to improve neck wrinkles that has recently been attracting attention is Skin boosters RE2O and RE2O Fine that help skin regenerationIt is. Although the two products are of the same type, the particle sizes are different, so the applied area, effect, and purpose of use are different. In particular, RE2O Fine is evaluated as an effective option for improving overall aging around the neck, as it can cover not only neck wrinkles but also the area under and around the eyes.
In this article, the director of Live Hip Clinic takes a closer look at the characteristics and differences between RE2O and RE2O Fine, how the difference in particle size affects the treatment results, and which product is more suitable for your neck wrinkles.
About RE2O
The basic concept of skin booster that helps skin regeneration
RE2O is an ECM (extracellular matrix) skin booster product that promotes the skin's self-regenerative ability. It is a preparation in the form of fine particles containing skin structural ingredients. It is injected into the dermal layer to help improve skin elasticity and regeneration at the same time. Gradual improvement of skin texture and reduction of wrinkles over time rather than immediate lifting or volume effectAiming for.
The basic version of RE2O is mainly used for skin regeneration and overall elasticity improvement in the general facial area, and its relatively large particles make it suitable for application to larger areas such as cheekbones, cheeks, and forehead. Since the skin condition gradually improves after the treatment, rather than dramatic changes over a short period of time, Results that naturally improve over 2 weeks to 1 monthIt is common to expect .
One of the characteristics of RE2O is Almost no downtimeThe point is. There may be slight redness or swelling immediately after the procedure, but it usually normalizes within the same day or the next day and has little effect on daily life. In this regard, it is an easy procedure to consider even for patients with busy schedules or many social activities.
Additionally, RE2O Easy to maintain regularlyThere is an advantage to this. You can maintain your skin in good condition by receiving a retouch treatment every six months, and this preventative approach helps delay skin aging in the long term.
RE2O vs RE2O Fine
Differences in application area and effect caused by differences in particle size
The most fundamental difference between RE2O and RE2O Fine is Particle size of formulationIt is in While RE2O has a relatively large particle size and is evenly distributed over a wide range of areas, RE2O Fine is designed to process the particles much finer so that they can be precisely injected into thin and sensitive areas of the skin.
The particle size is relatively large, making it suitable for treating a wide range of areas. It is mainly used to improve skin in large areas such as the entire face, cheeks, forehead, and around the nose, and is effective in cases where overall loss of elasticity and wrinkles appear together. The advantage is that ECM ingredients can cover a wide range of areas while strengthening the skin structure.
By finely processing particles Precise treatment for areas with thin and detailed skin, such as neck wrinkles, under the eyes, and around the eyesSpecialized in The fine ECM particles are evenly distributed over the top layer of the skin, making it possible to improve fine wrinkles more effectively. In particular, RE2O Fine's high suitability for improving neck wrinkles is recognized. The more detailed the area, the more sophisticated treatment is required, and the particle characteristics of the Fine version play a big role in this case.
Another feature of RE2O Fine is More precise injection depth controlThe point is that this is possible. The depth of injection is very important in delicate areas such as neck wrinkles or around the eyes, and the fine particles can be placed exactly at the required depth, so you can expect more natural and uniform results. Especially when you need to improve fine wrinkles under the eyes and sagging around the eyes at the same time, RE2O Fine's attention to detail can make a big difference.
By type
Selection criteria for RE2O and RE2O Fine according to the characteristics of neck wrinkles
Not all neck wrinkles appear the same way. Which version is more effective will depend on the depth, width, and skin elasticity of the wrinkles, so it is important to first understand the characteristics of your neck wrinkles.
- If you have many fine wrinkle lines and dry skin
RE2O Fine is the best choice. This is because the fine particles provide moisture to the skin layer and fill in fine wrinkles at the same time. You can expect natural results centered on improving skin texture rather than immediate lifting. - If there is a decrease in elasticity of the entire face and wrinkles on the neck
After treating the face with RE2O, you can consider a combined method of additional treatment with RE2O Fine on the neck area. This is a method that utilizes differences in particle size to produce results optimized for each area. - If you have deep neck wrinkles
It is recommended to use RE2O Fine in sufficient doses. Fine particles penetrate and fill deep wrinkles, while simultaneously improving the elasticity of the surrounding skin. In some cases, additional retouching may be required. - If you want to improve the neck, under the eyes, and around the eyes at the same time
RE2O Fine has the advantage of covering not only neck wrinkles but also under and around the eyes. Because the skin properties around the neck and eyes are similar, the same microparticle formulation is effective in both areas. The entire neck area can be treated with one treatment. - If you want continuous management and prevention
RE2O Fine is easy to maintain regularly. A maintenance treatment once every six months can be used to slow down the progression of neck wrinkles and prevent further worsening. Ideal for a long-term neck wrinkle management strategy. - If you want to experience the effects of the treatment gradually
Both RE2O series provide gradual improvement over 2 weeks to 1 month, making them ideal for those who prefer natural improvement over rapid change. In particular, the natural result is that neck wrinkles are gently alleviated rather than changing noticeably.
Before treatment
Things to check in advance before the procedure
The RE2O procedure is a relatively simple procedure, but the results and recovery may vary depending on prior preparation. In particular, since the neck area naturally has sensitive and thin skin, prior care is even more important.
- If you are taking any medications (especially anticoagulants or anti-inflammatory drugs), be sure to inform your medical staff in advance.
- It is recommended to refrain from drinking alcohol for 2-3 days before the procedure, and smoking can also affect the speed of recovery, so it is recommended to reduce it.
- Since the skin in the neck area is particularly prone to dryness, it is recommended to keep it well moisturized for a few days before the procedure.
- If you have acne or inflammation in the treatment area, inform the medical staff in advance and receive consultation.
- It is recommended to avoid exposure to strong ultraviolet rays or extreme temperature changes.
- Getting enough sleep, maintaining a similar physical condition as usual, and undergoing the procedure will help with recovery.
Procedure
General flow from consultation to follow-up observation
The RE2O procedure follows a clear process of consultation, procedure, and follow-up care. If you understand in advance what each step involves, you can reduce anxiety about the procedure and expect more effective results.
- 1:1 consultation with director
This is the step to accurately understand the characteristics of the neck wrinkles, skin condition, and the purpose and expectations of the procedure. Analyze the wrinkle pattern of the neck area and decide which of RE2O or RE2O Fine is more suitable and to what area to be treated. At this stage, it is important to organize all your questions.
- Pre-examination and skin analysis
A skin analysis is performed to accurately determine the current condition of the neck skin. It is used to determine the treatment dose and method by evaluating the depth of wrinkles, skin elasticity, and degree of dryness.
- superficial anesthesia
Superficial anesthesia is administered to minimize any discomfort you may feel during the injection. In most cases, local anesthesia is sufficient, and there is little pain during the procedure.
- RE2O treatment
It is precisely injected into the dermal layer of the neck area using a fine cannula. The medical staff carefully adjusts the injection angle and depth according to the depth and direction of the wrinkles, creating natural and uniform results. The time required is approximately 10 to 20 minutes depending on the area and dose.
- Progress observation and management
After the procedure, we observe gradual improvement in the skin over 2 weeks to 1 month. If necessary, you will receive management direction through additional consultation, and the timing of retouching treatment will be determined after 6 months.
After care
Management guidelines to maximize post-procedure effects and minimize side effects
The RE2O procedure has the advantage of having virtually no downtime, but proper post-treatment care greatly determines the final result. In particular, the neck area requires special attention as it is an area that moves frequently in daily life and is exposed to ultraviolet rays.
- Minor swelling or redness may appear immediately after the procedure, but most cases normalize within the same day or two.
- On the day of the procedure, it is recommended to avoid excessive neck movements (nodding your head frequently or bending over).
- Minimize exposure to direct sunlight on the treatment area and be sure to apply sunscreen when going out.
- Avoid drinking alcohol, saunas, saunas, and strenuous exercise on the day of the procedure and for the next two days.
- Avoid washing your face with hot water or rubbing it with a rough towel. Wash your face gently with lukewarm water.
- Please refrain from using cosmetics that are irritating to the treatment area (scrubs, peels, products with high concentration of vitamin C, etc.) for one week.
- Since the skin around the neck is more delicate, perform skin care with a gentler touch than usual.
- Adequate water intake and moisturizing management are important for recovery and lasting effects.
Clinic checklist
Checkpoints for choosing a trustworthy clinic
Check the professionalism of medical staff
- Sufficient clinical experience and performance related to neck wrinkle surgery
- In-depth understanding of the differences between RE2O and RE2O Fine and the characteristics of each product
- Micro-injection technique in the neck and around the eyes
- Ability to create a personalized treatment plan
Fidelity of consultation
- Whether the causes and characteristics of neck wrinkles are accurately diagnosed and explained
- Clear notice of the differences between RE2O and RE2O Fine, limitations of each product, and expected recovery process
- Providing optimal products and dosages tailored to individual skin conditions and goals
- Honest explanation of side effects and precautions and guidance on response measures
safety management standards
- Check whether genuine RE2O is used (excluding counterfeit products)
- Sterilization management standards for surgical instruments
- Whether to establish a system for emergency contact after the procedure
- Follow-up and regular follow-up plans
RE2O is a relatively simple procedure, but due to the delicate nature of the neck area, the injection technique and aesthetic sense of the clinician are important factors in determining natural results. We recommend that you receive consultation from several specialists and choose a medical team you can trust.
Common questions
Frequently Asked Questions About RE2O Treatment
- What exactly is the difference between RE2O and RE2O Fine?
- The biggest difference is the particle size. RE2O has relatively large particles and is suitable for treating a wide range of areas, while RE2O Fine has fine particles and is designed to be applied precisely to detailed areas such as neck wrinkles, under the eyes, and around the eyes. The Fine version can fill in finer wrinkles.
- Which is better for neck wrinkle treatment: RE2O or RE2O Fine?
- If your goal is to improve neck wrinkles, RE2O Fine is more suitable. The fine particles can more effectively improve delicate wrinkles on the neck, and have the advantage of covering under and around the eyes at the same time.
- When can I resume my daily activities after RE2O Fine treatment?
- In most cases, you can resume your daily activities the day after the procedure. There may be slight swelling or redness, but it usually normalizes within the next day. However, it is recommended to avoid actions that excessively move or stimulate the neck for a few days. Bruising varies depending on whether the treatment method is needle or cannula, but LivHip Clinic mainly uses the cannula method, which is characteristic of less bruising.
- When will the effects of RE2O treatment be seen?
- There is little change immediately after the procedure, but it gradually improves over 2 weeks to 1 month. Although there are individual differences, most people experience notable improvement after about 3 weeks.
- How long do the treatment effects last?
- It usually lasts 6 to 12 months. If you want to maintain the effect, it is recommended to undergo a retouch treatment once every six months.
- Is the procedure impossible if I have a certain skin disease?
- Active infections, some autoimmune diseases, and severe keloid constitution may limit the procedure. If you have an underlying disease, you must inform the medical staff during a prior consultation and confirm your suitability.
- How should I take skin care after the procedure?
- Focus on moisturizing and blocking UV rays for one week immediately after the procedure. It is important to avoid irritating ingredients (vitamin C, retinol, scrub, etc.), and to provide gentle cleansing and sufficient moisture. It is okay to return to your usual skin care routine two weeks after the procedure.
- Can multiple areas be treated at once?
- It is possible. RE2O can treat a wide range of areas, and RE2O Fine can treat not only the neck wrinkles but also the area under the eyes and around the eyes at once. However, the treatment time may vary depending on the dose and area.
- Should I undergo RE2O treatment regularly?
- Additional treatments are recommended every 6 to 12 months to maintain effectiveness. Since the cycle may vary depending on the individual's recovery speed and skin characteristics, it is recommended that you follow the guidance of your medical staff.





