There are several methods recommended by a dermatologist for the purpose of “skin regeneration” or “skin elasticity” improvement. Among them, many people are confused between skin boosters and regenerative injections that use components of one's own blood because they have something in common: they are both carried out through injections.
The two methods are fundamentally different in the ingredients used and how they work. In this article, we'll break down the differences between the two approaches to help you understand which direction may be better for your skin concerns. Please make your final choice after checking your condition through medical consultation.
Key differences
The most fundamental difference between the two approaches
Side by side
Item-by-item comparison
- Ingredients used
skin booster: Manufactured external ingredients such as hyaluronic acid, PDRN, growth factor mixture, vitamins, etc.
plasma regeneration: Platelet-rich plasma isolated from your own blood (autologous origin) - main purpose
skin booster: Moisture replenishment, skin gloss, skin texture improvement, elasticity assistance
plasma regeneration: Stimulates skin regeneration ability, induces collagen synthesis, supports tissue recovery - When the effect occurs
skin booster: You can feel the moisture and gloss changes relatively quickly.
plasma regeneration: Collagen production is a gradual process that occurs over several weeks to months. - Consideration of Immune Response
skin booster: Depending on the product, sensitivity to external ingredients may need to be checked.
plasma regeneration: Because it is a component isolated from one’s own blood, the risk of immune rejection is low. - Preparation before procedure
skin booster: No separate blood collection process
plasma regeneration: Same-day blood collection and centrifugation process required
Which for what
Reference direction for each type of skin concern (decided after consultation with medical staff)
The information below is a general reference standard, and the appropriate method may vary depending on your skin condition, age, and purpose.
Be sure to check with an expert.
- If your main concerns are lack of skin moisture and dryness
- If you want to improve skin gloss relatively quickly
- If you are looking for light care focused on hydration
- If you do not want to undergo a blood draw process
- If your main concerns are decreased skin regeneration and elasticity
- When there is damage to the dermal layer, such as acne scars or dents
- If you want to use your own resources without injecting external ingredients
- If you want to assist recovery after laser/radiofrequency treatment
Types of skin boosters
Skin boosters also have different purposes depending on their ingredients.
The term skin booster is a broad category that includes a variety of ingredients and methods. Depending on the main ingredient, its purpose is slightly different.
- Based on hyaluronic acid — The main purpose is to replenish moisture within the skin. Used for immediate moisturizing and gloss improvement
- PDRN (polydeoxyribonucleotide) — Salmon-derived DNA component used to promote tissue recovery and regeneration. Juberuk, etc. fall into this category.
- growth factor mixture — A product that combines several growth factors and aims to stimulate skin regeneration signals.
- Vitamin and amino acid complex — Used to supply skin nutrition and manage overall skin condition
Which skin booster is right for you depends on the type of skin concern and current condition. Rather than judging based on the name or ingredients alone, it is better to consult with an expert.
Common questions
Frequently Asked Questions
- Can I have both procedures on the same day?
- In some cases, it is possible to do both on the same day, and in other cases, it is recommended to space them out. Depending on the skin condition and characteristics of each procedure, the medical staff in charge will guide the order and interval.
- Are skin boosters and fillers different?
- Yes, it's different. Fillers are mainly used to fill volume or adjust contour and have a high viscosity. Skin boosters are dispersed within the skin and are used to help hydrate and regenerate, and have a low viscosity.
- Are plasma regeneration injections painful?
- There is a tingling sensation similar to that of a regular blood test when blood is drawn, and there may be temporary pain during injection. The procedure is performed with minimal discomfort through the use of anesthetic cream.
- Which procedure is better?
- It is important to find a method that suits you rather than a better method. Since the purposes and principles of the two methods are different, it is recommended that you decide with a specialist based on your skin concerns and condition.





